Use UniProt P9WFK7 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3879870 Target Snapshot
N-acetyltransferase Eis · SINGLE PROTEIN · Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
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As of 2026-09-13Protein identity stays anchored to UniProt P9WFK7. Use UniProt P9WFK7 as the stable identity anchor, then attach disease evidence before program review.
N-acetyltransferase Eis
Review this target as N-acetyltransferase Eis, mapped to UniProt P9WFK7. Sequence length is 402 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats N-acetyltransferase Eis as ChEMBL target CHEMBL3879870, mapped to UniProt P9WFK7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | N-acetyltransferase Eis |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| UniProt | P9WFK7 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | N-acetyltransferase Eis |
| UniProt Accession | P9WFK7 |
| Component Type | Protein |
| Sequence Length | 402 aa |
N-acetyltransferase Eis
How to read this target
Review this target as N-acetyltransferase Eis, mapped to UniProt P9WFK7. Sequence length is 402 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3931964 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL3931070 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL3911185 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL3963272 | 7.25 | IC50 | 56.0 | Preclinical |
| CHEMBL3900481 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL1410785 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL3909504 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL5573832 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL3950034 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL3967657 | 6.64 | IC50 | 230.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 17 assays, 85 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 47 | 5.7 |
| assay format | 2 | 17 | 6.1 |
| cell-based format | 2 | 21 | 5.5 |