MT4 · CELL-LINE · Homo sapiens
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MT4
Review this target as MT4.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats MT4 as ChEMBL target CHEMBL388. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | MT4 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as MT4.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL314298 | 10.8 | IC50 | 0.016 | Preclinical |
| CHEMBL83462 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL314758 | 9.82 | IC50 | 0.15 | Preclinical |
| CHEMBL206031 | 9.66 | IC50 | 0.22 | Clinical |
| CHEMBL71728 | 9.52 | EC50 | 0.3 | Preclinical |
| CHEMBL172850 | 9.4 | EC50 | 0.4 | Preclinical |
| CHEMBL70442 | 9.4 | EC50 | 0.4 | Preclinical |
| CHEMBL70517 | 9.4 | EC50 | 0.4 | Preclinical |
| CHEMBL176930 | 9.32 | EC50 | 0.48 | Preclinical |
| CHEMBL414640 | 9.24 | EC50 | 0.57 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1,153 | 1,532 | 6.3 |
| organism-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 451 | 115 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 64 | 13 | 5.2 |