Dipeptidyl peptidase 4 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P28843. Use UniProt P28843 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28843 as the stable identity anchor, then attach disease evidence before program review.
Dipeptidyl peptidase 4
Review this target as Dipeptidyl peptidase 4, mapped to UniProt P28843. Sequence length is 760 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dipeptidyl peptidase 4 as ChEMBL target CHEMBL3883, mapped to UniProt P28843. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Dipeptidyl peptidase 4 is the right protein anchor across sources, using UniProt P28843 as the stable mapping.
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| Preferred Name | Dipeptidyl peptidase 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P28843 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dipeptidyl peptidase 4 |
| UniProt Accession | P28843 |
| Component Type | Protein |
| Sequence Length | 760 aa |
Dipeptidyl peptidase 4
Review this target as Dipeptidyl peptidase 4, mapped to UniProt P28843. Sequence length is 760 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL237500 | 9.92 | IC50 | 0.12 | Approved |
| CHEMBL5859631 | 9.32 | IC50 | 0.474 | Preclinical |
| CHEMBL5968543 | 9.3 | IC50 | 0.498 | Preclinical |
| CHEMBL5993878 | 9.25 | IC50 | 0.564 | Preclinical |
| CHEMBL5411114 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL4463027 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL4593371 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL385517 | 8.72 | IC50 | 1.9 | Approved |
| CHEMBL4452661 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5914544 | 8.69 | IC50 | 2.03 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 16 | 32 | 7.7 |
| cell-free format | 5 | 24 | 7.6 |
| organism-based format | 4 | 2 | 7.6 |
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 23 | 0 | — |
| assay format | 1 | 0 | — |