CREB-binding protein/Histone acetyltransferase p300 · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q09472. Use UniProt Q09472 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q09472 as the stable identity anchor, then attach disease evidence before program review.
Histone acetyltransferase p300
Review this target as CREB-binding protein/Histone acetyltransferase p300, mapped to UniProt Q09472. ChEMBL maps the protein component as Histone acetyltransferase p300. Sequence length is 2414 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CREB-binding protein/Histone acetyltransferase p300 as ChEMBL target CHEMBL3883300, mapped to UniProt Q09472. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | CREB-binding protein/Histone acetyltransferase p300 |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | Q09472 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone acetyltransferase p300 |
| UniProt Accession | Q09472 |
| Component Type | Protein |
| Sequence Length | 2414 aa |
Histone acetyltransferase p300
Review this target as CREB-binding protein/Histone acetyltransferase p300, mapped to UniProt Q09472. ChEMBL maps the protein component as Histone acetyltransferase p300. Sequence length is 2414 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5220994 | 8.5 | EC50 | 3.162 | Preclinical |
| CHEMBL5219667 | 8.2 | EC50 | 6.31 | Preclinical |
| CHEMBL4217213 | 8.18 | EC50 | 6.6 | Preclinical |
| CHEMBL5219177 | 8.1 | EC50 | 7.943 | Preclinical |
| CHEMBL3902514 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4095153 | 7.92 | EC50 | 12.0 | Preclinical |
| CHEMBL5219693 | 7.9 | EC50 | 12.59 | Preclinical |
| CHEMBL5220956 | 7.8 | EC50 | 15.85 | Preclinical |
| CHEMBL4208820 | 7.75 | EC50 | 18.0 | Preclinical |
| CHEMBL5090131 | 7.75 | Kd | 17.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 129 | 67 | 6.5 |
| protein format | 12 | 90 | 6.5 |
| assay format | 6 | 16 | 6.9 |
| subcellular format | 1 | 0 | — |
| tissue-based format | 1 | 0 | — |