Adenomatous polyposis coli protein/Transcription factor 7-like 2 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P25054. Use UniProt P25054 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25054 as the stable identity anchor, then attach disease evidence before program review.
Adenomatous polyposis coli protein
Review this target as Adenomatous polyposis coli protein/Transcription factor 7-like 2, mapped to UniProt P25054. ChEMBL maps the protein component as Adenomatous polyposis coli protein. Sequence length is 2843 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenomatous polyposis coli protein/Transcription factor 7-like 2 as ChEMBL target CHEMBL3885511, mapped to UniProt P25054. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenomatous polyposis coli protein/Transcription factor 7-like 2 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P25054 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenomatous polyposis coli protein |
| UniProt Accession | P25054 |
| Component Type | Protein |
| Sequence Length | 2843 aa |
Adenomatous polyposis coli protein
Review this target as Adenomatous polyposis coli protein/Transcription factor 7-like 2, mapped to UniProt P25054. ChEMBL maps the protein component as Adenomatous polyposis coli protein. Sequence length is 2843 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2323033 | 5.08 | Ki | 8300.0 | Preclinical |
| CHEMBL460433 | 4.27 | Ki | 54000.0 | Preclinical |
| CHEMBL578512 | 4.18 | Ki | 66000.0 | Preclinical |
| CHEMBL2323029 | 4.16 | Ki | 69000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 2 | 8 | 4.3 |