Bile acid receptor/Retinoic acid receptor RXR-alpha · PROTEIN COMPLEX · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P28700. Use UniProt P28700 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28700 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor RXR-alpha
Review this target as Bile acid receptor/Retinoic acid receptor RXR-alpha, mapped to UniProt P28700. ChEMBL maps the protein component as Retinoic acid receptor RXR-alpha. Sequence length is 467 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bile acid receptor/Retinoic acid receptor RXR-alpha as ChEMBL target CHEMBL3885529, mapped to UniProt P28700. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Bile acid receptor/Retinoic acid receptor RXR-alpha |
| Target Type | PROTEIN COMPLEX |
| Organism | Mus musculus |
| UniProt | P28700 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor RXR-alpha |
| UniProt Accession | P28700 |
| Component Type | Protein |
| Sequence Length | 467 aa |
Retinoic acid receptor RXR-alpha
Review this target as Bile acid receptor/Retinoic acid receptor RXR-alpha, mapped to UniProt P28700. ChEMBL maps the protein component as Retinoic acid receptor RXR-alpha. Sequence length is 467 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL434750 | 6.07 | EC50 | 850.0 | Preclinical |
| CHEMBL1915763 | 5.6 | EC50 | 2500.0 | Preclinical |
| CHEMBL1915761 | 5.3 | EC50 | 5000.0 | Preclinical |
| CHEMBL240597 | 4.78 | EC50 | 16800.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 4 | 5.4 |