Use UniProt Q9NQB0 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3885533 Target Snapshot
Cadherin-1/Transcription factor 7-like 2 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NQB0. Use UniProt Q9NQB0 as the stable identity anchor, then attach disease evidence before program review.
Transcription factor 7-like 2
Review this target as Cadherin-1/Transcription factor 7-like 2, mapped to UniProt Q9NQB0. ChEMBL maps the protein component as Transcription factor 7-like 2. Sequence length is 619 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Cadherin-1/Transcription factor 7-like 2 as ChEMBL target CHEMBL3885533, mapped to UniProt Q9NQB0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cadherin-1/Transcription factor 7-like 2 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | Q9NQB0 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcription factor 7-like 2 |
| UniProt Accession | Q9NQB0 |
| Component Type | Protein |
| Sequence Length | 619 aa |
Transcription factor 7-like 2
How to read this target
Review this target as Cadherin-1/Transcription factor 7-like 2, mapped to UniProt Q9NQB0. ChEMBL maps the protein component as Transcription factor 7-like 2. Sequence length is 619 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2323033 | 4.92 | Ki | 12000.0 | Preclinical |
| CHEMBL460433 | 4.89 | Ki | 13000.0 | Preclinical |
| CHEMBL578512 | 4.89 | Ki | 13000.0 | Preclinical |
| CHEMBL2323029 | 4.55 | Ki | 28000.0 | Preclinical |
| CHEMBL2323028 | 4.23 | Ki | 59000.0 | Preclinical |
| CHEMBL2323031 | 4.17 | Ki | 68000.0 | Preclinical |
| CHEMBL2323032 | 4.0 | Ki | 100000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 4 assays, 19 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 19 | 4.5 |