Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha · PROTEIN COMPLEX · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q09472. Use UniProt Q09472 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q09472 as the stable identity anchor, then attach disease evidence before program review.
Histone acetyltransferase p300
Review this target as Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha, mapped to UniProt Q09472. ChEMBL maps the protein component as Histone acetyltransferase p300. Sequence length is 2414 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha as ChEMBL target CHEMBL3885588, mapped to UniProt Q09472. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha is the right protein anchor across sources, using UniProt Q09472 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q09472 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone acetyltransferase p300 |
| UniProt Accession | Q09472 |
| Component Type | Protein |
| Sequence Length | 2414 aa |
Histone acetyltransferase p300
Review this target as Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha, mapped to UniProt Q09472. ChEMBL maps the protein component as Histone acetyltransferase p300. Sequence length is 2414 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1940227 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL499593 | 6.27 | IC50 | 540.0 | Preclinical |
| CHEMBL1823895 | 6.23 | IC50 | 590.0 | Preclinical |
| CHEMBL4542925 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL4574165 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL4080730 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4555191 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL4524475 | 5.46 | Ki | 3500.0 | Preclinical |
| CHEMBL5272424 | 5.04 | IC50 | 9200.0 | Preclinical |
| CHEMBL1089316 | 4.9 | IC50 | 12500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 12 | 14 | 5.2 |
| cell-based format | 2 | 1 | 6.3 |