Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P42338. Use UniProt P42338 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P42338 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Review this target as Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, mapped to UniProt P42338. ChEMBL maps the protein component as Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform. Sequence length is 1070 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform as ChEMBL target CHEMBL3885615, mapped to UniProt P42338. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform is the right protein anchor across sources, using UniProt P42338 as the stable mapping.
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| Preferred Name | Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P42338 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
| UniProt Accession | P42338 |
| Component Type | Protein |
| Sequence Length | 1070 aa |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Review this target as Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, mapped to UniProt P42338. ChEMBL maps the protein component as Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform. Sequence length is 1070 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4749200 | 6.76 | IC50 | 174.0 | Preclinical |
| CHEMBL2216870 | 6.24 | IC50 | 579.0 | Approved |
| CHEMBL4760138 | 5.58 | IC50 | 2641.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 2 | 1 | 6.2 |
| assay format | 1 | 2 | 6.2 |