Chymotrypsin-like elastase family member 2A · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P00774. Use UniProt P00774 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00774 as the stable identity anchor, then attach disease evidence before program review.
Chymotrypsin-like elastase family member 2A
Review this target as Chymotrypsin-like elastase family member 2A, mapped to UniProt P00774. Sequence length is 271 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Chymotrypsin-like elastase family member 2A as ChEMBL target CHEMBL3888, mapped to UniProt P00774. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Chymotrypsin-like elastase family member 2A |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P00774 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chymotrypsin-like elastase family member 2A |
| UniProt Accession | P00774 |
| Component Type | Protein |
| Sequence Length | 271 aa |
Chymotrypsin-like elastase family member 2A
Review this target as Chymotrypsin-like elastase family member 2A, mapped to UniProt P00774. Sequence length is 271 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL84758 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL431207 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL24983 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL310133 | 4.96 | IC50 | 11000.0 | Preclinical |
| CHEMBL418925 | 4.43 | IC50 | 37000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 5 | 5.7 |