Carbonic anhydrase · SINGLE PROTEIN · Methanobacterium thermoautotrophicum
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As of 2026-09-14Protein identity stays anchored to UniProt Q50565. Use UniProt Q50565 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q50565 as the stable identity anchor, then attach disease evidence before program review.
Carbonic anhydrase
Review this target as Carbonic anhydrase, mapped to UniProt Q50565. Sequence length is 176 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carbonic anhydrase as ChEMBL target CHEMBL3926, mapped to UniProt Q50565. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Carbonic anhydrase is the right protein anchor across sources, using UniProt Q50565 as the stable mapping.
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| Preferred Name | Carbonic anhydrase |
| Target Type | SINGLE PROTEIN |
| Organism | Methanobacterium thermoautotrophicum |
| UniProt | Q50565 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carbonic anhydrase |
| UniProt Accession | Q50565 |
| Component Type | Protein |
| Sequence Length | 176 aa |
Carbonic anhydrase
Review this target as Carbonic anhydrase, mapped to UniProt Q50565. Sequence length is 176 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL18 | 5.27 | Ki | 5350.0 | Approved |
| CHEMBL20 | 4.92 | Ki | 12100.0 | Approved |
| CHEMBL6852 | 4.84 | Ki | 14300.0 | Preclinical |
| CHEMBL220492 | 4.63 | Ki | 23500.0 | Approved |
| CHEMBL7087 | 4.59 | Ki | 25700.0 | Preclinical |
| CHEMBL419 | 4.54 | Ki | 28500.0 | Approved |
| CHEMBL218490 | 4.51 | Ki | 30700.0 | Approved |
| CHEMBL19 | 4.49 | Ki | 32100.0 | Approved |
| CHEMBL118 | 4.42 | Ki | 38500.0 | Approved |
| CHEMBL418 | 4.3 | Ki | 50000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 36 | 4.5 |