Serine/threonine-protein kinase 16 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O75716. Use UniProt O75716 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O75716 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase 16
Review this target as Serine/threonine-protein kinase 16, mapped to UniProt O75716. Sequence length is 305 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase 16 as ChEMBL target CHEMBL3938, mapped to UniProt O75716. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase 16 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O75716 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase 16 |
| UniProt Accession | O75716 |
| Component Type | Protein |
| Sequence Length | 305 aa |
Serine/threonine-protein kinase 16
Review this target as Serine/threonine-protein kinase 16, mapped to UniProt O75716. Sequence length is 305 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL475251 | 8.77 | Kd | 1.7 | Clinical |
| CHEMBL1287853 | 8.18 | Kd | 6.6 | Approved |
| CHEMBL5633837 | 7.96 | Kd | 11.0 | Preclinical |
| CHEMBL5653589 | 7.78 | Kd | 16.67 | Preclinical |
| CHEMBL1908395 | 7.75 | Kd | 18.0 | Preclinical |
| CHEMBL502835 | 7.75 | Kd | 18.0 | Approved |
| CHEMBL603469 | 7.72 | Kd | 19.0 | Clinical |
| CHEMBL516312 | 7.62 | Kd | 24.0 | Preclinical |
| CHEMBL1908397 | 7.54 | Kd | 29.0 | Preclinical |
| CHEMBL4571548 | 7.11 | Ki | 78.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 173 | 42 | 6.5 |
| assay format | 30 | 23 | 6.5 |
| subcellular format | 22 | 22 | 6.0 |
| cell-based format | 17 | 2 | 6.7 |