Substance-P receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt P30547. Use UniProt P30547 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30547 as the stable identity anchor, then attach disease evidence before program review.
Substance-P receptor
Review this target as Substance-P receptor, mapped to UniProt P30547. Sequence length is 407 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Substance-P receptor as ChEMBL target CHEMBL3942, mapped to UniProt P30547. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Substance-P receptor is the right protein anchor across sources, using UniProt P30547 as the stable mapping.
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| Preferred Name | Substance-P receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P30547 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Substance-P receptor |
| UniProt Accession | P30547 |
| Component Type | Protein |
| Sequence Length | 407 aa |
Substance-P receptor
Review this target as Substance-P receptor, mapped to UniProt P30547. Sequence length is 407 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL38763 | 10.72 | IC50 | 0.019 | Preclinical |
| CHEMBL235363 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL441225 | 9.77 | Ki | 0.17 | Preclinical |
| CHEMBL288600 | 9.51 | IC50 | 0.31 | Preclinical |
| CHEMBL2114310 | 9.49 | Kd | 0.32 | Preclinical |
| CHEMBL66635 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL16192 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL156128 | 9.3 | Kd | 0.5012 | Preclinical |
| CHEMBL66441 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL303803 | 9.22 | Ki | 0.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 76 | 61 | 7.4 |
| assay format | 10 | 73 | 7.8 |
| organism-based format | 6 | 0 | — |
| cell membrane format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 25 | 43 | 7.1 |
| single protein format | 19 | 80 | 7.2 |
| cell membrane format | 6 | 46 | 8.1 |
| organism-based format | 3 | 0 | — |
| assay format | 2 | 3 | 8.7 |