Fructose-1,6-bisphosphatase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P09467. Use UniProt P09467 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P09467 as the stable identity anchor, then attach disease evidence before program review.
Fructose-1,6-bisphosphatase 1
Review this target as Fructose-1,6-bisphosphatase 1, mapped to UniProt P09467. Sequence length is 338 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Fructose-1,6-bisphosphatase 1 as ChEMBL target CHEMBL3975, mapped to UniProt P09467. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Fructose-1,6-bisphosphatase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P09467 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fructose-1,6-bisphosphatase 1 |
| UniProt Accession | P09467 |
| Component Type | Protein |
| Sequence Length | 338 aa |
Fructose-1,6-bisphosphatase 1
Review this target as Fructose-1,6-bisphosphatase 1, mapped to UniProt P09467. Sequence length is 338 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL589266 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1173125 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL462979 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL597891 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL1173126 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL597692 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL457189 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL462978 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL457400 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL463183 | 8.22 | IC50 | 6.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 57 | 510 | 6.3 |
| single protein format | 47 | 65 | 6.0 |
| tissue-based format | 7 | 58 | 6.0 |
| cell-based format | 5 | 23 | 5.8 |