Dipeptidyl peptidase 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UHL4. Use UniProt Q9UHL4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UHL4 as the stable identity anchor, then attach disease evidence before program review.
Dipeptidyl peptidase 2
Review this target as Dipeptidyl peptidase 2, mapped to UniProt Q9UHL4. Sequence length is 492 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dipeptidyl peptidase 2 as ChEMBL target CHEMBL3976, mapped to UniProt Q9UHL4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dipeptidyl peptidase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UHL4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dipeptidyl peptidase 2 |
| UniProt Accession | Q9UHL4 |
| Component Type | Protein |
| Sequence Length | 492 aa |
Dipeptidyl peptidase 2
Review this target as Dipeptidyl peptidase 2, mapped to UniProt Q9UHL4. Sequence length is 492 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5723377 | 10.09 | Ki | 0.082 | Preclinical |
| CHEMBL98869 | 10.09 | Ki | 0.082 | Preclinical |
| CHEMBL5723377 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL98801 | 9.66 | IC50 | 0.22 | Preclinical |
| CHEMBL98869 | 9.66 | IC50 | 0.22 | Preclinical |
| CHEMBL98762 | 9.64 | IC50 | 0.23 | Preclinical |
| CHEMBL418979 | 9.41 | IC50 | 0.39 | Preclinical |
| CHEMBL99506 | 9.41 | IC50 | 0.39 | Preclinical |
| CHEMBL99247 | 9.39 | IC50 | 0.41 | Preclinical |
| CHEMBL194354 | 9.32 | IC50 | 0.48 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 107 | 1,043 | 5.4 |
| cell-based format | 19 | 43 | 4.7 |
| assay format | 6 | 64 | 5.4 |
| cell-free format | 1 | 12 | 5.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 1 | 9.7 |
| cell-based format | 2 | 1 | 9.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |