Tyrosine-protein kinase Fer · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P16591. Use UniProt P16591 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16591 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase Fer
Review this target as Tyrosine-protein kinase Fer, mapped to UniProt P16591. Sequence length is 822 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase Fer as ChEMBL target CHEMBL3982, mapped to UniProt P16591. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein kinase Fer |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P16591 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase Fer |
| UniProt Accession | P16591 |
| Component Type | Protein |
| Sequence Length | 822 aa |
Tyrosine-protein kinase Fer
Review this target as Tyrosine-protein kinase Fer, mapped to UniProt P16591. Sequence length is 822 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.69 | IC50 | 0.203 | Preclinical |
| CHEMBL5597957 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL5598347 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL5598005 | 9.38 | IC50 | 0.42 | Preclinical |
| CHEMBL4461851 | 9.31 | IC50 | 0.49 | Preclinical |
| CHEMBL5596211 | 9.31 | IC50 | 0.49 | Preclinical |
| CHEMBL3545311 | 8.89 | IC50 | 1.3 | Approved |
| CHEMBL5188373 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL509032 | 8.85 | Kd | 1.4 | Preclinical |
| CHEMBL461876 | 8.8 | Ki | 1.585 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 224 | 55 | 7.0 |
| assay format | 47 | 19 | 7.5 |
| cell-based format | 44 | 5 | 7.0 |
| subcellular format | 27 | 34 | 6.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 130 | 6.6 |