Sepiapterin reductase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P35270. Use UniProt P35270 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35270 as the stable identity anchor, then attach disease evidence before program review.
Sepiapterin reductase
Review this target as Sepiapterin reductase, mapped to UniProt P35270. Sequence length is 261 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sepiapterin reductase as ChEMBL target CHEMBL3988583, mapped to UniProt P35270. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sepiapterin reductase is the right protein anchor across sources, using UniProt P35270 as the stable mapping.
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| Preferred Name | Sepiapterin reductase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P35270 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sepiapterin reductase |
| UniProt Accession | P35270 |
| Component Type | Protein |
| Sequence Length | 261 aa |
Sepiapterin reductase
Review this target as Sepiapterin reductase, mapped to UniProt P35270. Sequence length is 261 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4483011 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4483412 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4483582 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4483610 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4483674 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4513401 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4513411 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4513597 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4513705 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4516020 | 9.0 | IC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 964 | 8.0 |
| cell-based format | 2 | 874 | 6.6 |