S-methyl-5'-thioinosine phosphorylase · SINGLE PROTEIN · Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 /JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
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As of 2026-09-14Protein identity stays anchored to UniProt Q9HZK1. Use UniProt Q9HZK1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9HZK1 as the stable identity anchor, then attach disease evidence before program review.
S-methyl-5'-thioinosine phosphorylase
Review this target as S-methyl-5'-thioinosine phosphorylase, mapped to UniProt Q9HZK1. Sequence length is 245 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats S-methyl-5'-thioinosine phosphorylase as ChEMBL target CHEMBL3988593, mapped to UniProt Q9HZK1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | S-methyl-5'-thioinosine phosphorylase |
| Target Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 /JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
| UniProt | Q9HZK1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | S-methyl-5'-thioinosine phosphorylase |
| UniProt Accession | Q9HZK1 |
| Component Type | Protein |
| Sequence Length | 245 aa |
S-methyl-5'-thioinosine phosphorylase
Review this target as S-methyl-5'-thioinosine phosphorylase, mapped to UniProt Q9HZK1. Sequence length is 245 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4108769 | 10.46 | Ki | 0.035 | Preclinical |
| CHEMBL474328 | 10.46 | Ki | 0.035 | Preclinical |
| CHEMBL4115457 | 10.14 | Ki | 0.072 | Preclinical |
| CHEMBL4107138 | 10.12 | Ki | 0.076 | Preclinical |
| CHEMBL473929 | 10.12 | Ki | 0.076 | Preclinical |
| CHEMBL462398 | 10.02 | Ki | 0.096 | Preclinical |
| CHEMBL3914407 | 9.47 | Ki | 0.34 | Preclinical |
| CHEMBL514795 | 9.47 | Ki | 0.34 | Preclinical |
| CHEMBL3926568 | 8.92 | Ki | 1.21 | Preclinical |
| CHEMBL3644483 | 7.72 | Ki | 19.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 10 | 9.6 |