Hypoxanthine-guanine-xanthine phosphoribosyltransferase · SINGLE PROTEIN · Plasmodium falciparum (isolate FCR-3 / Gambia)
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As of 2026-09-14Protein identity stays anchored to UniProt P20035. Use UniProt P20035 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20035 as the stable identity anchor, then attach disease evidence before program review.
Hypoxanthine-guanine-xanthine phosphoribosyltransferase
Review this target as Hypoxanthine-guanine-xanthine phosphoribosyltransferase, mapped to UniProt P20035. Sequence length is 231 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Hypoxanthine-guanine-xanthine phosphoribosyltransferase as ChEMBL target CHEMBL3988608, mapped to UniProt P20035. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Hypoxanthine-guanine-xanthine phosphoribosyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum (isolate FCR-3 / Gambia) |
| UniProt | P20035 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Hypoxanthine-guanine-xanthine phosphoribosyltransferase |
| UniProt Accession | P20035 |
| Component Type | Protein |
| Sequence Length | 231 aa |
Hypoxanthine-guanine-xanthine phosphoribosyltransferase
Review this target as Hypoxanthine-guanine-xanthine phosphoribosyltransferase, mapped to UniProt P20035. Sequence length is 231 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5573402 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL5591537 | 7.22 | Ki | 60.0 | Preclinical |
| CHEMBL5563998 | 6.3 | Ki | 500.0 | Preclinical |
| CHEMBL5565343 | 5.7 | Ki | 2000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 4 | 6.8 |