Dihydropteroate synthase · SINGLE PROTEIN · Escherichia coli K-12
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As of 2026-09-14Protein identity stays anchored to UniProt P0AC13. Use UniProt P0AC13 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0AC13 as the stable identity anchor, then attach disease evidence before program review.
Dihydropteroate synthase
Review this target as Dihydropteroate synthase, mapped to UniProt P0AC13. Sequence length is 282 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dihydropteroate synthase as ChEMBL target CHEMBL4032, mapped to UniProt P0AC13. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dihydropteroate synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
| UniProt | P0AC13 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dihydropteroate synthase |
| UniProt Accession | P0AC13 |
| Component Type | Protein |
| Sequence Length | 282 aa |
Dihydropteroate synthase
Review this target as Dihydropteroate synthase, mapped to UniProt P0AC13. Sequence length is 282 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL158543 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL159139 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL159048 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL422884 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL158993 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL351250 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL442357 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL55866 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL348892 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL158793 | 5.68 | IC50 | 2100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 26 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 19 | 5.6 |