Carnitine O-palmitoyltransferase 2, mitochondrial · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P18886. Use UniProt P18886 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P18886 as the stable identity anchor, then attach disease evidence before program review.
Carnitine O-palmitoyltransferase 2, mitochondrial
Review this target as Carnitine O-palmitoyltransferase 2, mitochondrial, mapped to UniProt P18886. Sequence length is 658 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carnitine O-palmitoyltransferase 2, mitochondrial as ChEMBL target CHEMBL4037, mapped to UniProt P18886. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Carnitine O-palmitoyltransferase 2, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P18886 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carnitine O-palmitoyltransferase 2, mitochondrial |
| UniProt Accession | P18886 |
| Component Type | Protein |
| Sequence Length | 658 aa |
Carnitine O-palmitoyltransferase 2, mitochondrial
Review this target as Carnitine O-palmitoyltransferase 2, mitochondrial, mapped to UniProt P18886. Sequence length is 658 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3431777 | 6.54 | IC50 | 290.6 | Preclinical |
| CHEMBL3431605 | 6.46 | IC50 | 344.8 | Preclinical |
| CHEMBL1231506 | 6.42 | IC50 | 380.0 | Clinical |
| CHEMBL3431737 | 6.32 | IC50 | 477.3 | Preclinical |
| CHEMBL3431735 | 6.3 | IC50 | 495.6 | Preclinical |
| CHEMBL3431736 | 6.27 | IC50 | 538.8 | Preclinical |
| CHEMBL3431801 | 6.19 | IC50 | 642.6 | Preclinical |
| CHEMBL3431602 | 6.17 | IC50 | 684.3 | Preclinical |
| CHEMBL3431739 | 6.15 | IC50 | 701.2 | Preclinical |
| CHEMBL2114397 | 6.1 | IC50 | 800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 177 | 4.9 |
| mitochondrion format | 3 | 2 | 5.1 |
| assay format | 1 | 0 | — |