Casein kinase II subunit alpha' · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P19784. Use UniProt P19784 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19784 as the stable identity anchor, then attach disease evidence before program review.
Casein kinase II subunit alpha'
Review this target as Casein kinase II subunit alpha', mapped to UniProt P19784. Sequence length is 350 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Casein kinase II subunit alpha' as ChEMBL target CHEMBL4070, mapped to UniProt P19784. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Casein kinase II subunit alpha' |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P19784 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Casein kinase II subunit alpha' |
| UniProt Accession | P19784 |
| Component Type | Protein |
| Sequence Length | 350 aa |
Casein kinase II subunit alpha'
Review this target as Casein kinase II subunit alpha', mapped to UniProt P19784. Sequence length is 350 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3699289 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL3699235 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL3699234 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL3699276 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL3699237 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL3699252 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL3699295 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL3699282 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL3699244 | 9.82 | IC50 | 0.15 | Preclinical |
| CHEMBL3699266 | 9.8 | IC50 | 0.16 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 196 | 161 | 7.7 |
| assay format | 30 | 40 | 6.4 |
| cell-based format | 26 | 90 | 6.8 |
| subcellular format | 15 | 53 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 143 | 1 | 5.8 |