Cathepsin G · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P08311. Use UniProt P08311 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08311 as the stable identity anchor, then attach disease evidence before program review.
Cathepsin G
Review this target as Cathepsin G, mapped to UniProt P08311. Sequence length is 255 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cathepsin G as ChEMBL target CHEMBL4071, mapped to UniProt P08311. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cathepsin G is the right protein anchor across sources, using UniProt P08311 as the stable mapping.
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| Preferred Name | Cathepsin G |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P08311 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cathepsin G |
| UniProt Accession | P08311 |
| Component Type | Protein |
| Sequence Length | 255 aa |
Cathepsin G
Review this target as Cathepsin G, mapped to UniProt P08311. Sequence length is 255 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL453539 | 9.82 | Ki | 0.15 | Preclinical |
| CHEMBL418050 | 9.76 | Ki | 0.174 | Preclinical |
| CHEMBL285285 | 9.73 | Ki | 0.187 | Preclinical |
| CHEMBL4592765 | 9.59 | Ki | 0.26 | Preclinical |
| CHEMBL47394 | 9.41 | IC50 | 0.39 | Preclinical |
| CHEMBL2448441 | 9.36 | Ki | 0.437 | Preclinical |
| CHEMBL4061897 | 9.05 | Ki | 0.89 | Preclinical |
| CHEMBL290577 | 9.04 | Ki | 0.916 | Preclinical |
| CHEMBL4077874 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL108540 | 8.85 | IC50 | 1.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 143 | 235 | 6.1 |
| cell-based format | 6 | 5 | 6.7 |
| tissue-based format | 1 | 1 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 1 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |