Beta-adrenergic receptor kinase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P25098. Use UniProt P25098 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25098 as the stable identity anchor, then attach disease evidence before program review.
Beta-adrenergic receptor kinase 1
Review this target as Beta-adrenergic receptor kinase 1, mapped to UniProt P25098. Sequence length is 689 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-adrenergic receptor kinase 1 as ChEMBL target CHEMBL4079, mapped to UniProt P25098. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-adrenergic receptor kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P25098 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-adrenergic receptor kinase 1 |
| UniProt Accession | P25098 |
| Component Type | Protein |
| Sequence Length | 689 aa |
Beta-adrenergic receptor kinase 1
Review this target as Beta-adrenergic receptor kinase 1, mapped to UniProt P25098. Sequence length is 689 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1738878 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL4073882 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL4072828 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL4086046 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL1738878 | 8.7 | Kd | 1.99 | Preclinical |
| CHEMBL3716385 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3718650 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL4095659 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3719041 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL3716440 | 8.49 | IC50 | 3.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 144 | 271 | 6.0 |
| assay format | 27 | 94 | 6.9 |
| cell-based format | 20 | 73 | 6.8 |
| subcellular format | 7 | 5 | 5.4 |
| tissue-based format | 3 | 0 | — |
| cell membrane format | 2 | 1 | 6.5 |