Cytochrome P450 2A5 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P20852. Use UniProt P20852 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20852 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 2A5
Review this target as Cytochrome P450 2A5, mapped to UniProt P20852. Sequence length is 494 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 2A5 as ChEMBL target CHEMBL4085, mapped to UniProt P20852. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 2A5 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P20852 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 2A5 |
| UniProt Accession | P20852 |
| Component Type | Protein |
| Sequence Length | 494 aa |
Cytochrome P450 2A5
Review this target as Cytochrome P450 2A5, mapped to UniProt P20852. Sequence length is 494 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL179669 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL359657 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL178090 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL179704 | 6.12 | IC50 | 750.0 | Preclinical |
| CHEMBL361153 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL369285 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL190982 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL195036 | 5.85 | IC50 | 1399.59 | Preclinical |
| CHEMBL194983 | 5.77 | IC50 | 1698.24 | Preclinical |
| CHEMBL195407 | 5.66 | IC50 | 2197.86 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 56 | 5.1 |