1-deoxy-D-xylulose 5-phosphate reductoisomerase · SINGLE PROTEIN · Escherichia coli K-12
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As of 2026-09-14Protein identity stays anchored to UniProt P45568. Use UniProt P45568 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P45568 as the stable identity anchor, then attach disease evidence before program review.
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Review this target as 1-deoxy-D-xylulose 5-phosphate reductoisomerase, mapped to UniProt P45568. Sequence length is 398 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 1-deoxy-D-xylulose 5-phosphate reductoisomerase as ChEMBL target CHEMBL4091, mapped to UniProt P45568. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
| UniProt | P45568 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| UniProt Accession | P45568 |
| Component Type | Protein |
| Sequence Length | 398 aa |
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Review this target as 1-deoxy-D-xylulose 5-phosphate reductoisomerase, mapped to UniProt P45568. Sequence length is 398 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2164257 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL203125 | 7.7 | IC50 | 19.95 | Clinical |
| CHEMBL205338 | 7.55 | IC50 | 28.18 | Preclinical |
| CHEMBL258981 | 7.32 | IC50 | 48.0 | Preclinical |
| CHEMBL204406 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL607359 | 7.27 | IC50 | 53.7 | Preclinical |
| CHEMBL204106 | 7.23 | IC50 | 59.0 | Preclinical |
| CHEMBL606521 | 7.19 | IC50 | 64.57 | Preclinical |
| CHEMBL3341763 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL1651835 | 7.0 | IC50 | 99.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 27 | 91 | 5.9 |