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Target Snapshot

CHEMBL4094 Target Snapshot

1-deoxy-D-xylulose 5-phosphate reductoisomerase · SINGLE PROTEIN · Synechocystis sp. (strain PCC 6803 / Kazusa)

7Compounds
3Assays
0Approved Drugs
6.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q55663. Use UniProt Q55663 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q55663 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats 1-deoxy-D-xylulose 5-phosphate reductoisomerase as ChEMBL target CHEMBL4094, mapped to UniProt Q55663. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
1-deoxy-D-xylulose 5-phosphate reductoisomerase
SINGLE PROTEIN · Synechocystis sp. (strain PCC 6803 / Kazusa)
As of 2026-09-14
ChEMBL target ID
CHEMBL4094
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q55663
1-deoxy-D-xylulose 5-phosphate reductoisomerase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether 1-deoxy-D-xylulose 5-phosphate reductoisomerase is the right protein anchor across sources, using UniProt Q55663 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Label1-deoxy-D-xylulose 5-phosphate reductoisomerase
UniProt AccessionQ55663
Component TypeProtein
Sequence Length394 aa

1-deoxy-D-xylulose 5-phosphate reductoisomerase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as 1-deoxy-D-xylulose 5-phosphate reductoisomerase, mapped to UniProt Q55663. Sequence length is 394 aa.

Mapped IDQ55663
Review name1-deoxy-D-xylulose 5-phosphate reductoisomerase
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa)
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

KI6.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL203125 7.68 Ki 21.0 Clinical
CHEMBL1161705 4.52 Ki 30000.0 Preclinical
CHEMBL1161703 4.05 Ki 90000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3
Total Assays
6
Tested Compounds
1
Assay Types
Binding — 3 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 3 6 5.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine