5-hydroxytryptamine receptor 1D · SINGLE PROTEIN · Sus scrofa
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P79400. Use UniProt P79400 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P79400 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 1D
Review this target as 5-hydroxytryptamine receptor 1D, mapped to UniProt P79400. Sequence length is 291 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 1D as ChEMBL target CHEMBL4105, mapped to UniProt P79400. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether 5-hydroxytryptamine receptor 1D is the right protein anchor across sources, using UniProt P79400 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | 5-hydroxytryptamine receptor 1D |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | P79400 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 1D |
| UniProt Accession | P79400 |
| Component Type | Protein |
| Sequence Length | 291 aa |
5-hydroxytryptamine receptor 1D
Review this target as 5-hydroxytryptamine receptor 1D, mapped to UniProt P79400. Sequence length is 291 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL39435 | 9.6 | IC50 | 0.2512 | Preclinical |
| CHEMBL39317 | 9.5 | IC50 | 0.3162 | Preclinical |
| CHEMBL289489 | 9.3 | IC50 | 0.5012 | Preclinical |
| CHEMBL288880 | 9.1 | IC50 | 0.7943 | Preclinical |
| CHEMBL39331 | 9.1 | IC50 | 0.7943 | Preclinical |
| CHEMBL262652 | 8.9 | IC50 | 1.259 | Preclinical |
| CHEMBL40126 | 8.9 | IC50 | 1.259 | Preclinical |
| CHEMBL37629 | 8.8 | IC50 | 1.585 | Preclinical |
| CHEMBL37462 | 8.7 | IC50 | 1.995 | Preclinical |
| CHEMBL38104 | 8.7 | IC50 | 1.995 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 37 | 7.3 |
| single protein format | 5 | 49 | 5.2 |
| cell membrane format | 4 | 40 | 8.2 |
| tissue-based format | 1 | 2 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |