Use UniProt Q06330 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4105709 Target Snapshot
Recombining binding protein suppressor of hairless · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q06330. Use UniProt Q06330 as the stable identity anchor, then attach disease evidence before program review.
Recombining binding protein suppressor of hairless
Review this target as Recombining binding protein suppressor of hairless, mapped to UniProt Q06330. Sequence length is 500 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Recombining binding protein suppressor of hairless as ChEMBL target CHEMBL4105709, mapped to UniProt Q06330. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Recombining binding protein suppressor of hairless |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q06330 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Recombining binding protein suppressor of hairless |
| UniProt Accession | Q06330 |
| Component Type | Protein |
| Sequence Length | 500 aa |
Recombining binding protein suppressor of hairless
How to read this target
Review this target as Recombining binding protein suppressor of hairless, mapped to UniProt Q06330. Sequence length is 500 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4111071 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL4112855 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL4114579 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL3921166 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL4111904 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL4114126 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL3896414 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL4107767 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL4107070 | 8.42 | IC50 | 3.8 | Preclinical |
| CHEMBL4112577 | 8.4 | IC50 | 4.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 8 assays, 29 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 0 | — |
| cell-based format | 2 | 29 | 8.1 |