Diacylglycerol kinase alpha · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P23743. Use UniProt P23743 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23743 as the stable identity anchor, then attach disease evidence before program review.
Diacylglycerol kinase alpha
Review this target as Diacylglycerol kinase alpha, mapped to UniProt P23743. Sequence length is 735 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Diacylglycerol kinase alpha as ChEMBL target CHEMBL4105787, mapped to UniProt P23743. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Diacylglycerol kinase alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P23743 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Diacylglycerol kinase alpha |
| UniProt Accession | P23743 |
| Component Type | Protein |
| Sequence Length | 735 aa |
Diacylglycerol kinase alpha
Review this target as Diacylglycerol kinase alpha, mapped to UniProt P23743. Sequence length is 735 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5768187 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5781357 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL6027746 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5424446 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5818523 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5915983 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL5845562 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5919576 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5849375 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5408449 | 7.82 | IC50 | 15.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 30 | 15 | 5.5 |
| single protein format | 8 | 113 | 6.6 |
| subcellular format | 1 | 0 | — |