COP9 signalosome complex subunit 5 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q92905. Use UniProt Q92905 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q92905 as the stable identity anchor, then attach disease evidence before program review.
COP9 signalosome complex subunit 5
Review this target as COP9 signalosome complex subunit 5, mapped to UniProt Q92905. Sequence length is 334 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats COP9 signalosome complex subunit 5 as ChEMBL target CHEMBL4105809, mapped to UniProt Q92905. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether COP9 signalosome complex subunit 5 is the right protein anchor across sources, using UniProt Q92905 as the stable mapping.
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| Preferred Name | COP9 signalosome complex subunit 5 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q92905 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | COP9 signalosome complex subunit 5 |
| UniProt Accession | Q92905 |
| Component Type | Protein |
| Sequence Length | 334 aa |
COP9 signalosome complex subunit 5
Review this target as COP9 signalosome complex subunit 5, mapped to UniProt Q92905. Sequence length is 334 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4528101 | 8.24 | IC50 | 5.8 | Preclinical |
| CHEMBL4447716 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL274056 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL9470 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL28457 | 6.57 | IC50 | 270.0 | Preclinical |
| CHEMBL4088568 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL403516 | 6.37 | IC50 | 430.0 | Preclinical |
| CHEMBL4096289 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL9416 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL4101230 | 5.8 | IC50 | 1600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 16 | 5.2 |
| single protein format | 4 | 25 | 5.3 |