Use UniProt P07741 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4105819 Target Snapshot
Adenine phosphoribosyltransferase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P07741. Use UniProt P07741 as the stable identity anchor, then attach disease evidence before program review.
Adenine phosphoribosyltransferase
Review this target as Adenine phosphoribosyltransferase, mapped to UniProt P07741. Sequence length is 180 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Adenine phosphoribosyltransferase as ChEMBL target CHEMBL4105819, mapped to UniProt P07741. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Adenine phosphoribosyltransferase is the right protein anchor across sources, using UniProt P07741 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Adenine phosphoribosyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07741 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenine phosphoribosyltransferase |
| UniProt Accession | P07741 |
| Component Type | Protein |
| Sequence Length | 180 aa |
Adenine phosphoribosyltransferase
How to read this target
Review this target as Adenine phosphoribosyltransferase, mapped to UniProt P07741. Sequence length is 180 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 7.88 | Kd | 13.08 | Preclinical |
| CHEMBL2105728 | 7.54 | Kd | 29.0 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 7.9 |
| subcellular format | 1 | 1 | 7.5 |