Histone-lysine N-methyltransferase SETD1B · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UPS6. Use UniProt Q9UPS6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UPS6 as the stable identity anchor, then attach disease evidence before program review.
Histone-lysine N-methyltransferase SETD1B
Review this target as Histone-lysine N-methyltransferase SETD1B, mapped to UniProt Q9UPS6. Sequence length is 1966 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone-lysine N-methyltransferase SETD1B as ChEMBL target CHEMBL4105837, mapped to UniProt Q9UPS6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Histone-lysine N-methyltransferase SETD1B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UPS6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone-lysine N-methyltransferase SETD1B |
| UniProt Accession | Q9UPS6 |
| Component Type | Protein |
| Sequence Length | 1966 aa |
Histone-lysine N-methyltransferase SETD1B
Review this target as Histone-lysine N-methyltransferase SETD1B, mapped to UniProt Q9UPS6. Sequence length is 1966 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1232461 | 7.35 | Kd | 45.0 | Clinical |
| CHEMBL1232461 | 7.22 | IC50 | 60.0 | Clinical |
| CHEMBL4465202 | 4.85 | IC50 | 14000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 1 | 7.3 |
| assay format | 5 | 1 | 4.8 |