Meprin A subunit beta · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q16820. Use UniProt Q16820 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q16820 as the stable identity anchor, then attach disease evidence before program review.
Meprin A subunit beta
Review this target as Meprin A subunit beta, mapped to UniProt Q16820. Sequence length is 701 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Meprin A subunit beta as ChEMBL target CHEMBL4105879, mapped to UniProt Q16820. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Meprin A subunit beta |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q16820 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Meprin A subunit beta |
| UniProt Accession | Q16820 |
| Component Type | Protein |
| Sequence Length | 701 aa |
Meprin A subunit beta
Review this target as Meprin A subunit beta, mapped to UniProt Q16820. Sequence length is 701 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4096803 | 8.1 | Ki | 8.0 | Preclinical |
| CHEMBL1253351 | 7.66 | Ki | 22.0 | Preclinical |
| CHEMBL4209993 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL4205925 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL4216076 | 7.31 | IC50 | 49.0 | Preclinical |
| CHEMBL4078433 | 7.24 | IC50 | 57.0 | Preclinical |
| CHEMBL4105563 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL4206683 | 7.12 | IC50 | 76.0 | Preclinical |
| CHEMBL4217240 | 7.11 | IC50 | 77.0 | Preclinical |
| CHEMBL4207946 | 6.75 | IC50 | 177.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 4 | 6.2 |
| assay format | 2 | 87 | 5.7 |