14-3-3 protein zeta/delta · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P63104. Use UniProt P63104 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P63104 as the stable identity anchor, then attach disease evidence before program review.
14-3-3 protein zeta/delta
Review this target as 14-3-3 protein zeta/delta, mapped to UniProt P63104. Sequence length is 245 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 14-3-3 protein zeta/delta as ChEMBL target CHEMBL4105899, mapped to UniProt P63104. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 14-3-3 protein zeta/delta is the right protein anchor across sources, using UniProt P63104 as the stable mapping.
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| Preferred Name | 14-3-3 protein zeta/delta |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P63104 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 14-3-3 protein zeta/delta |
| UniProt Accession | P63104 |
| Component Type | Protein |
| Sequence Length | 245 aa |
14-3-3 protein zeta/delta
Review this target as 14-3-3 protein zeta/delta, mapped to UniProt P63104. Sequence length is 245 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 8.34 | Kd | 4.526 | Preclinical |
| CHEMBL4217121 | 8.14 | Kd | 7.3 | Preclinical |
| CHEMBL4206466 | 8.05 | Kd | 9.0 | Preclinical |
| CHEMBL4218471 | 7.75 | Kd | 18.0 | Preclinical |
| CHEMBL4096939 | 7.42 | Kd | 38.0 | Preclinical |
| CHEMBL4247970 | 7.39 | Kd | 41.0 | Preclinical |
| CHEMBL4063253 | 7.23 | Kd | 59.0 | Preclinical |
| CHEMBL4096528 | 7.0 | Kd | 99.0 | Preclinical |
| CHEMBL4080446 | 6.99 | Kd | 103.0 | Preclinical |
| CHEMBL4061432 | 6.46 | Kd | 350.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 16 | 23 | 6.4 |
| cell-based format | 4 | 2 | 5.0 |
| assay format | 3 | 3 | 5.9 |