Signal peptide peptidase-like 2B · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8TCT7. Use UniProt Q8TCT7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TCT7 as the stable identity anchor, then attach disease evidence before program review.
Signal peptide peptidase-like 2B
Review this target as Signal peptide peptidase-like 2B, mapped to UniProt Q8TCT7. Sequence length is 592 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Signal peptide peptidase-like 2B as ChEMBL target CHEMBL4105912, mapped to UniProt Q8TCT7. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Signal peptide peptidase-like 2B is the right protein anchor across sources, using UniProt Q8TCT7 as the stable mapping.
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| Preferred Name | Signal peptide peptidase-like 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TCT7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Signal peptide peptidase-like 2B |
| UniProt Accession | Q8TCT7 |
| Component Type | Protein |
| Sequence Length | 592 aa |
Signal peptide peptidase-like 2B
Review this target as Signal peptide peptidase-like 2B, mapped to UniProt Q8TCT7. Sequence length is 592 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4759048 | 6.57 | IC50 | 270.0 | Preclinical |
| CHEMBL4069936 | 6.37 | IC50 | 430.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 2 | 6.5 |