Diacylglycerol kinase zeta · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13574. Use UniProt Q13574 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13574 as the stable identity anchor, then attach disease evidence before program review.
Diacylglycerol kinase zeta
Review this target as Diacylglycerol kinase zeta, mapped to UniProt Q13574. Sequence length is 928 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Diacylglycerol kinase zeta as ChEMBL target CHEMBL4105942, mapped to UniProt Q13574. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Diacylglycerol kinase zeta |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13574 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Diacylglycerol kinase zeta |
| UniProt Accession | Q13574 |
| Component Type | Protein |
| Sequence Length | 928 aa |
Diacylglycerol kinase zeta
Review this target as Diacylglycerol kinase zeta, mapped to UniProt Q13574. Sequence length is 928 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5424446 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5768187 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5851336 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL6044573 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL5921368 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL5868935 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5860953 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL5828405 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL5906768 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL5931568 | 7.89 | IC50 | 13.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 228 | 6.4 |
| cell-based format | 2 | 7 | 5.9 |
| assay format | 1 | 0 | — |