Signal peptide peptidase-like 2A · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9JJF9. Use UniProt Q9JJF9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9JJF9 as the stable identity anchor, then attach disease evidence before program review.
Signal peptide peptidase-like 2A
Review this target as Signal peptide peptidase-like 2A, mapped to UniProt Q9JJF9. Sequence length is 523 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Signal peptide peptidase-like 2A as ChEMBL target CHEMBL4105948, mapped to UniProt Q9JJF9. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Signal peptide peptidase-like 2A is the right protein anchor across sources, using UniProt Q9JJF9 as the stable mapping.
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| Preferred Name | Signal peptide peptidase-like 2A |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9JJF9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Signal peptide peptidase-like 2A |
| UniProt Accession | Q9JJF9 |
| Component Type | Protein |
| Sequence Length | 523 aa |
Signal peptide peptidase-like 2A
Review this target as Signal peptide peptidase-like 2A, mapped to UniProt Q9JJF9. Sequence length is 523 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4759048 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL4076827 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL4100749 | 6.92 | IC50 | 121.0 | Preclinical |
| CHEMBL4069936 | 6.86 | IC50 | 137.0 | Preclinical |
| CHEMBL4077007 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL4077336 | 6.3 | IC50 | 496.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 6 | 6.7 |
| single protein format | 2 | 3 | 7.3 |
| tissue-based format | 1 | 0 | — |