Carbonic anhydrase 1 · SINGLE PROTEIN · Equus caballus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P00917. Use UniProt P00917 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00917 as the stable identity anchor, then attach disease evidence before program review.
Carbonic anhydrase 1
Review this target as Carbonic anhydrase 1, mapped to UniProt P00917. Sequence length is 261 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carbonic anhydrase 1 as ChEMBL target CHEMBL4105955, mapped to UniProt P00917. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Carbonic anhydrase 1 is the right protein anchor across sources, using UniProt P00917 as the stable mapping.
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| Preferred Name | Carbonic anhydrase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Equus caballus |
| UniProt | P00917 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carbonic anhydrase 1 |
| UniProt Accession | P00917 |
| Component Type | Protein |
| Sequence Length | 261 aa |
Carbonic anhydrase 1
Review this target as Carbonic anhydrase 1, mapped to UniProt P00917. Sequence length is 261 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2010994 | 10.42 | Kd | 0.038 | Preclinical |
| CHEMBL2011156 | 9.27 | Kd | 0.54 | Preclinical |
| CHEMBL3797385 | 9.15 | Kd | 0.7 | Preclinical |
| CHEMBL2443188 | 9.12 | Kd | 0.76 | Preclinical |
| CHEMBL3798446 | 8.85 | Kd | 1.4 | Preclinical |
| CHEMBL3799945 | 8.62 | Kd | 2.4 | Preclinical |
| CHEMBL3799577 | 8.37 | Kd | 4.3 | Preclinical |
| CHEMBL2443189 | 8.17 | Kd | 6.8 | Preclinical |
| CHEMBL2011155 | 6.96 | Kd | 110.0 | Preclinical |
| CHEMBL3799296 | 6.7 | Kd | 200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 11 | 8.6 |