Use UniProt K4CF70 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4105968 Target Snapshot
Fatty acid hydroperoxide lyase, chloroplastic · SINGLE PROTEIN · Solanum lycopersicum
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As of 2026-09-13Protein identity stays anchored to UniProt K4CF70. Use UniProt K4CF70 as the stable identity anchor, then attach disease evidence before program review.
Fatty acid hydroperoxide lyase, chloroplastic
Review this target as Fatty acid hydroperoxide lyase, chloroplastic, mapped to UniProt K4CF70. Sequence length is 476 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Fatty acid hydroperoxide lyase, chloroplastic as ChEMBL target CHEMBL4105968, mapped to UniProt K4CF70. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Fatty acid hydroperoxide lyase, chloroplastic |
| Target Type | SINGLE PROTEIN |
| Organism | Solanum lycopersicum |
| UniProt | K4CF70 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fatty acid hydroperoxide lyase, chloroplastic |
| UniProt Accession | K4CF70 |
| Component Type | Protein |
| Sequence Length | 476 aa |
Fatty acid hydroperoxide lyase, chloroplastic
How to read this target
Review this target as Fatty acid hydroperoxide lyase, chloroplastic, mapped to UniProt K4CF70. Sequence length is 476 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2272315 | 4.87 | Kd | 13500.0 | Preclinical |
| CHEMBL2272315 | 4.41 | IC50 | 39000.0 | Preclinical |
| CHEMBL2272319 | 4.34 | IC50 | 46000.0 | Preclinical |
| CHEMBL52 | 4.3 | IC50 | 50000.0 | Preclinical |
| CHEMBL91 | 4.19 | IC50 | 65000.0 | Approved |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 4 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 4 | 4.4 |