Lysyl oxidase homolog 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P58215. Use UniProt P58215 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P58215 as the stable identity anchor, then attach disease evidence before program review.
Lysyl oxidase homolog 3
Review this target as Lysyl oxidase homolog 3, mapped to UniProt P58215. Sequence length is 753 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysyl oxidase homolog 3 as ChEMBL target CHEMBL4105989, mapped to UniProt P58215. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Lysyl oxidase homolog 3 is the right protein anchor across sources, using UniProt P58215 as the stable mapping.
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| Preferred Name | Lysyl oxidase homolog 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P58215 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysyl oxidase homolog 3 |
| UniProt Accession | P58215 |
| Component Type | Protein |
| Sequence Length | 753 aa |
Lysyl oxidase homolog 3
Review this target as Lysyl oxidase homolog 3, mapped to UniProt P58215. Sequence length is 753 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4457578 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL964 | 7.03 | IC50 | 93.0 | Approved |
| CHEMBL120563 | 6.96 | IC50 | 110.0 | Clinical |
| CHEMBL1618272 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL4068784 | 6.67 | IC50 | 214.0 | Preclinical |
| CHEMBL4568508 | 6.07 | IC50 | 860.0 | Preclinical |
| CHEMBL4063337 | 5.93 | IC50 | 1170.0 | Preclinical |
| CHEMBL4092740 | 5.91 | IC50 | 1220.0 | Preclinical |
| CHEMBL4457897 | 5.91 | IC50 | 1220.0 | Preclinical |
| CHEMBL4444163 | 5.9 | IC50 | 1250.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 22 | 5.6 |
| single protein format | 2 | 4 | 6.1 |