c-Myc/c-Max · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P01106. Use UniProt P01106 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P01106 as the stable identity anchor, then attach disease evidence before program review.
Myc proto-oncogene protein
Review this target as c-Myc/c-Max, mapped to UniProt P01106. ChEMBL maps the protein component as Myc proto-oncogene protein. Sequence length is 454 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats c-Myc/c-Max as ChEMBL target CHEMBL4106127, mapped to UniProt P01106. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | c-Myc/c-Max |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P01106 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Myc proto-oncogene protein |
| UniProt Accession | P01106 |
| Component Type | Protein |
| Sequence Length | 454 aa |
Myc proto-oncogene protein
Review this target as c-Myc/c-Max, mapped to UniProt P01106. ChEMBL maps the protein component as Myc proto-oncogene protein. Sequence length is 454 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4238599 | 8.19 | Kd | 6.5 | Preclinical |
| CHEMBL201467 | 5.39 | IC50 | 4100.0 | Preclinical |
| CHEMBL4093782 | 5.34 | IC50 | 4600.0 | Preclinical |
| CHEMBL4086023 | 5.19 | IC50 | 6500.0 | Preclinical |
| CHEMBL4103943 | 5.0 | IC50 | 10000.0 | Preclinical |
| CHEMBL4066335 | 4.75 | IC50 | 18000.0 | Preclinical |
| CHEMBL255556 | 4.64 | IC50 | 23000.0 | Preclinical |
| CHEMBL3222133 | 4.54 | IC50 | 29000.0 | Preclinical |
| CHEMBL4780968 | 4.54 | EC50 | 29100.0 | Preclinical |
| CHEMBL1336889 | 4.48 | IC50 | 33000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 13 | 4.7 |
| protein format | 4 | 6 | 5.2 |
| assay format | 1 | 0 | — |