HSP60/HSP10 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P10809. Use UniProt P10809 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10809 as the stable identity anchor, then attach disease evidence before program review.
60 kDa heat shock protein, mitochondrial
Review this target as HSP60/HSP10, mapped to UniProt P10809. ChEMBL maps the protein component as 60 kDa heat shock protein, mitochondrial. Sequence length is 573 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HSP60/HSP10 as ChEMBL target CHEMBL4106131, mapped to UniProt P10809. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether HSP60/HSP10 is the right protein anchor across sources, using UniProt P10809 as the stable mapping.
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| Preferred Name | HSP60/HSP10 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P10809 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 60 kDa heat shock protein, mitochondrial |
| UniProt Accession | P10809 |
| Component Type | Protein |
| Sequence Length | 573 aa |
60 kDa heat shock protein, mitochondrial
Review this target as HSP60/HSP10, mapped to UniProt P10809. ChEMBL maps the protein component as 60 kDa heat shock protein, mitochondrial. Sequence length is 573 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1200712 | 6.77 | IC50 | 170.0 | Approved |
| CHEMBL4161583 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL1516388 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL496 | 5.89 | IC50 | 1300.0 | Approved |
| CHEMBL3115912 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL3115927 | 5.75 | IC50 | 1800.0 | Preclinical |
| CHEMBL15192 | 5.68 | IC50 | 2100.0 | Clinical |
| CHEMBL4167333 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL297453 | 5.64 | IC50 | 2300.0 | Clinical |
| CHEMBL1265 | 5.64 | IC50 | 2300.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 63 | 5.1 |
| cell-based format | 3 | 55 | 4.6 |
| mitochondrion format | 1 | 15 | 4.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 28 | 4.2 |