Rho GTPase Rac1/CDC42 · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P60953. Use UniProt P60953 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P60953 as the stable identity anchor, then attach disease evidence before program review.
Cell division control protein 42 homolog
Review this target as Rho GTPase Rac1/CDC42, mapped to UniProt P60953. ChEMBL maps the protein component as Cell division control protein 42 homolog. Sequence length is 191 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Rho GTPase Rac1/CDC42 as ChEMBL target CHEMBL4106177, mapped to UniProt P60953. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Rho GTPase Rac1/CDC42 is the right protein anchor across sources, using UniProt P60953 as the stable mapping.
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| Preferred Name | Rho GTPase Rac1/CDC42 |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P60953 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cell division control protein 42 homolog |
| UniProt Accession | P60953 |
| Component Type | Protein |
| Sequence Length | 191 aa |
Cell division control protein 42 homolog
Review this target as Rho GTPase Rac1/CDC42, mapped to UniProt P60953. ChEMBL maps the protein component as Cell division control protein 42 homolog. Sequence length is 191 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1619630 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL469 | 5.7 | IC50 | 2000.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 2 | 5.8 |