B2 bradykinin receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt O70526. Use UniProt O70526 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O70526 as the stable identity anchor, then attach disease evidence before program review.
B2 bradykinin receptor
Review this target as B2 bradykinin receptor, mapped to UniProt O70526. Sequence length is 372 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats B2 bradykinin receptor as ChEMBL target CHEMBL4111, mapped to UniProt O70526. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | B2 bradykinin receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | O70526 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | B2 bradykinin receptor |
| UniProt Accession | O70526 |
| Component Type | Protein |
| Sequence Length | 372 aa |
B2 bradykinin receptor
Review this target as B2 bradykinin receptor, mapped to UniProt O70526. Sequence length is 372 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL220596 | 10.4 | Kd | 0.03981 | Preclinical |
| CHEMBL1956722 | 10.2 | Kd | 0.0631 | Preclinical |
| CHEMBL2371961 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL2028850 | 10.05 | IC50 | 0.09 | Approved |
| CHEMBL2370160 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL113169 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL113963 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL205093 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL375689 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL375820 | 10.0 | Kd | 0.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 11 | 200 | 7.9 |
| tissue-based format | 9 | 33 | 8.0 |
| single protein format | 5 | 18 | 8.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 10 | 8 | 7.9 |
| tissue-based format | 4 | 36 | 7.2 |