Platelet-derived growth factor receptor beta · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q05030. Use UniProt Q05030 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q05030 as the stable identity anchor, then attach disease evidence before program review.
Platelet-derived growth factor receptor beta
Review this target as Platelet-derived growth factor receptor beta, mapped to UniProt Q05030. Sequence length is 1097 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Platelet-derived growth factor receptor beta as ChEMBL target CHEMBL4125, mapped to UniProt Q05030. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Platelet-derived growth factor receptor beta |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q05030 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Platelet-derived growth factor receptor beta |
| UniProt Accession | Q05030 |
| Component Type | Protein |
| Sequence Length | 1097 aa |
Platelet-derived growth factor receptor beta
Review this target as Platelet-derived growth factor receptor beta, mapped to UniProt Q05030. Sequence length is 1097 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3940697 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL2148124 | 8.74 | Kd | 1.8 | Preclinical |
| CHEMBL3975580 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL3904768 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3913766 | 8.44 | IC50 | 3.6 | Preclinical |
| CHEMBL3950278 | 8.1 | IC50 | 7.9 | Preclinical |
| CHEMBL3895824 | 8.06 | IC50 | 8.7 | Preclinical |
| CHEMBL3979322 | 8.04 | IC50 | 9.2 | Preclinical |
| CHEMBL3955987 | 8.02 | IC50 | 9.5 | Preclinical |
| CHEMBL3947262 | 7.99 | IC50 | 10.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 17 | 7.9 |
| single protein format | 1 | 1 | 8.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 22 | 5.5 |