Bifunctional epoxide hydrolase 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P34914. Use UniProt P34914 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P34914 as the stable identity anchor, then attach disease evidence before program review.
Bifunctional epoxide hydrolase 2
Review this target as Bifunctional epoxide hydrolase 2, mapped to UniProt P34914. Sequence length is 554 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bifunctional epoxide hydrolase 2 as ChEMBL target CHEMBL4140, mapped to UniProt P34914. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Bifunctional epoxide hydrolase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P34914 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bifunctional epoxide hydrolase 2 |
| UniProt Accession | P34914 |
| Component Type | Protein |
| Sequence Length | 554 aa |
Bifunctional epoxide hydrolase 2
Review this target as Bifunctional epoxide hydrolase 2, mapped to UniProt P34914. Sequence length is 554 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5415121 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL5427173 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL5592524 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL5428998 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL5430033 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL5564312 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL5424246 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL5433624 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL5435557 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL5433817 | 9.89 | IC50 | 0.13 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 29 | 358 | 7.6 |
| assay format | 5 | 69 | 7.4 |
| cell-based format | 2 | 4 | 8.5 |
| tissue-based format | 2 | 73 | 7.9 |
| microsome format | 1 | 3 | 8.8 |