Large neutral amino acids transporter small subunit 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q63016. Use UniProt Q63016 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q63016 as the stable identity anchor, then attach disease evidence before program review.
Large neutral amino acids transporter small subunit 1
Review this target as Large neutral amino acids transporter small subunit 1, mapped to UniProt Q63016. Sequence length is 512 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Large neutral amino acids transporter small subunit 1 as ChEMBL target CHEMBL4149, mapped to UniProt Q63016. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Large neutral amino acids transporter small subunit 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63016 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Large neutral amino acids transporter small subunit 1 |
| UniProt Accession | Q63016 |
| Component Type | Protein |
| Sequence Length | 512 aa |
Large neutral amino acids transporter small subunit 1
Review this target as Large neutral amino acids transporter small subunit 1, mapped to UniProt Q63016. Sequence length is 512 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL153149 | 7.1 | Ki | 79.0 | Preclinical |
| CHEMBL1084596 | 5.68 | Ki | 2100.0 | Preclinical |
| CHEMBL1084594 | 5.3 | Ki | 5000.0 | Preclinical |
| CHEMBL8708 | 5.11 | Ki | 7700.0 | Preclinical |
| CHEMBL345930 | 5.07 | Ki | 8500.0 | Preclinical |
| CHEMBL1082953 | 4.9 | Ki | 12500.0 | Preclinical |
| CHEMBL1084595 | 4.58 | Ki | 26000.0 | Preclinical |
| CHEMBL301523 | 4.26 | Ki | 55000.0 | Clinical |
| CHEMBL852 | 4.26 | Ki | 55000.0 | Approved |
| CHEMBL1085590 | 4.17 | Ki | 68000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 3 | 2 | 5.7 |
| assay format | 1 | 11 | 5.0 |