Enoyl-acyl-carrier protein reductase · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-13Protein identity stays anchored to UniProt Q965D5. Use UniProt Q965D5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q965D5 as the stable identity anchor, then attach disease evidence before program review.
Enoyl-acyl-carrier protein reductase
Review this target as Enoyl-acyl-carrier protein reductase, mapped to UniProt Q965D5. Sequence length is 432 aa.
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This review treats Enoyl-acyl-carrier protein reductase as ChEMBL target CHEMBL4150, mapped to UniProt Q965D5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Enoyl-acyl-carrier protein reductase |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | Q965D5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Enoyl-acyl-carrier protein reductase |
| UniProt Accession | Q965D5 |
| Component Type | Protein |
| Sequence Length | 432 aa |
Enoyl-acyl-carrier protein reductase
Review this target as Enoyl-acyl-carrier protein reductase, mapped to UniProt Q965D5. Sequence length is 432 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL849 | 10.28 | Ki | 0.05206 | Approved |
| CHEMBL228097 | 8.38 | Ki | 4.2 | Preclinical |
| CHEMBL297453 | 8.1 | Ki | 8.0 | Clinical |
| CHEMBL128000 | 7.85 | Ki | 14.0 | Preclinical |
| CHEMBL36327 | 7.8 | Ki | 16.0 | Preclinical |
| CHEMBL47386 | 7.75 | Ki | 17.56 | Preclinical |
| CHEMBL50 | 7.66 | Ki | 22.0 | Clinical |
| CHEMBL228097 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL260979 | 7.42 | IC50 | 38.0 | Preclinical |
| CHEMBL129451 | 7.4 | Ki | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 46 | 99 | 6.3 |
| cell-based format | 3 | 35 | 5.4 |
| assay format | 1 | 1 | 7.3 |