Urease · SINGLE PROTEIN · Canavalia ensiformis
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P07374. Use UniProt P07374 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07374 as the stable identity anchor, then attach disease evidence before program review.
Urease
Review this target as Urease, mapped to UniProt P07374. Sequence length is 840 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Urease as ChEMBL target CHEMBL4161, mapped to UniProt P07374. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Urease is the right protein anchor across sources, using UniProt P07374 as the stable mapping.
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| Preferred Name | Urease |
| Target Type | SINGLE PROTEIN |
| Organism | Canavalia ensiformis |
| UniProt | P07374 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Urease |
| UniProt Accession | P07374 |
| Component Type | Protein |
| Sequence Length | 840 aa |
Urease
Review this target as Urease, mapped to UniProt P07374. Sequence length is 840 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5186550 | 8.72 | IC50 | 1.91 | Preclinical |
| CHEMBL1549559 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL5199980 | 7.68 | Ki | 21.0 | Preclinical |
| CHEMBL399930 | 7.6 | Ki | 25.0 | Preclinical |
| CHEMBL5170974 | 7.53 | IC50 | 29.4 | Preclinical |
| CHEMBL5206478 | 7.45 | IC50 | 35.4 | Preclinical |
| CHEMBL5199980 | 7.41 | IC50 | 39.1 | Preclinical |
| CHEMBL3818469 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL4100084 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL5204803 | 7.24 | IC50 | 58.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 64 | 400 | 5.2 |